• About me

    Now

    I'm a Fellow of The Jane Coffin Childs Memorial Fund for Medical Research at UCLA in the Kosuri Lab. I recently developed a massively parallel sequencing assay to understand how small molecules interact with the receptors that mediate smell. More generally, I am interested in using next-gen sequencing and mathematical analysis to define and then engineer new genotype-phenotype relationships.

    Before

    From January to July 2018, I spent a stint helping start Octant Inc. which uses technology I developed in my post-doc to test drugs against medicinally relevant cell receptors in parallel. In May 2015, I finished my PhD at Harvard University in the Paulsson Lab. My thesis was on the control of mitochondrial DNA copy number, yeast polarity and RNA Polymerase dynamics. Before that, I received an A.B. in physics at Harvard College in 2007.

  • RESEARCH

    Massively multiplex measurements of phenotype-genotype relationship using deep sequencing.

    Replacing traditional assays with next-generation sequencing allowed us to measure the responses of large numbers of smell receptors to a chemical at the same time. Eventually, this type of data will allow us to predict which chemicals hit which receptors.

    Mitochondrial DNA copy number control

    How does mitochondrial DNA control replication to double each cell cycle and then divide between daughter cells at division? A paper on this work can be found here (or pdf). You can also read about it in my thesis.

  • Publications

    Eric M Jones*, Rishi Jajoo*, Daniel Cancilla, Nathan B Lubock, Jeff Wang, Megan Satyadi, Rocky Cheung, Claire de March, Hiroaki Matsunami, Sriram Kosuri

    bioRxiv 358739; https://doi.org/10.1101/358739 and in review

    (* Indicates shared first-authorship)

    Rishi Jajoo, Yoonseok Jung, Dann Huh, Matheus Viana, Susanne Rafelski, Michael Springer, and Johan Paulsson

    Science. 8 January 2016. Vol. 351 no. 6269 pp. 169-172
    DOI: 10.1126/science.aaa8714

    (pdf) (Supplement)

    Martin Lukačišin*, , Matthieu Landon* and Rishi Jajoo* PLoS ONE 12(3): e0174066. doi:10.1371/journal.pone.0174066 (2017)

    (* Indicates shared first-authorship)

    ( Indicates corresponding author)

    Kalin Vetsigian, Rishi Jajoo, Roy Kishony

    PLoS Biol 9(10): e1001184. doi:10.1371/journal.pbio.1001184 (2011)

  • CONTACT

    [rjajoo] [at] [gmail] [dot] [com]